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Lira Clinical REGEN PDRN+ Serum
A regenerative PDRN serum designed to calm, repair and strengthen skin while improving firmness, hydration, fine lines and loss of elasticity.
Lira Clinical REGEN PDRN+ Serum takes PDRN skincare a step further by combining PDRN (polydeoxyribonucleotide), a regenerative ingredient derived from purified salmon DNA, with Wild Salmon Stem Cell-CM, copper peptides and growth-factor technology.
This lightweight serum supports the skin’s natural repair processes while helping calm visible redness and inflammation, reinforce the skin barrier, and support collagen and elasticity. With continued use, skin looks smoother, firmer and more even, with improved hydration and a softened appearance of fine lines.
It’s especially helpful for skin that feels depleted, dehydrated or stressed by environmental exposure, as well as skin beginning to show changes in firmness, elasticity and texture.
Size: 1 oz
What Makes It Different
Many PDRN serums center primarily around PDRN. REGEN PDRN+ pairs it with Wild Salmon Stem Cell-CM, Lira Clinical’s biotechnology-derived conditioned media created from cultured wild salmon stem cells, along with copper peptides, EGF and additional peptides.
This multi-pathway approach supports the skin’s natural repair response while targeting fine lines, loss of firmness and elasticity, dehydration, redness and uneven tone.
And the serum’s distinctive blue color isn’t just for looks. It comes from Copper Tripeptide-1, a naturally blue peptide, rather than added blue dyes or colorants.
Key Ingredients
PDRN (Polydeoxyribonucleotide)
A regenerative ingredient derived from purified salmon DNA that supports the skin’s natural repair processes while helping promote collagen production and calm visible inflammation.
Wild Salmon Stem Cell-CM
Lira Clinical’s marine-derived conditioned-media technology, created from cultured wild salmon stem cells. It provides regenerative signaling components that support cellular renewal and help strengthen skin resilience.
Copper Tripeptide-1
A naturally blue copper peptide that gives REGEN PDRN+ Serum its distinctive blue color. It supports collagen and elastin to help improve the appearance of firmness and fine lines.
EGF + Peptide Complex
Oligopeptide-1 (EGF) supports skin renewal and barrier function, while additional peptides help support collagen and soften the appearance of expression lines.
Niacinamide
Supports the skin barrier while helping improve uneven tone, hydration and overall skin resilience.
Hyaluronic Acid
Attracts and retains moisture to help keep skin soft, smooth and hydrated.
How to Use
Apply 1–2 drops in the evening after cleansing. Allow the serum to fully absorb and dry before applying additional skincare products.
I prefer using REGEN PDRN+ at night, when the skin’s natural renewal and repair processes are more active.
Pila’s Tip
PDRN products can sometimes have a noticeable marine scent because of their salmon-derived ingredients. REGEN PDRN+ doesn’t have that strong marine scent at all. Instead, it has a light essential-oil scent from grapefruit and orange peel oils.
I especially like this serum for skin that is dehydrated, environmentally stressed or beginning to show fine lines and loss of firmness and elasticity. Its combination of PDRN, copper peptides and regenerative technology makes it an especially interesting addition to an evening skincare routine.
Pairs Well With
Green Envee Retinal Renewal Complex
One of my favorite pairings with REGEN PDRN+. Retinoids are incredibly effective for fine lines, texture and firmness, but the dryness and irritation they can cause can make them difficult to use consistently. REGEN PDRN+ brings PDRN, copper peptides, niacinamide and hyaluronic acid into the routine to support hydration, the skin barrier and natural repair processes while you get the benefits of retinal.
Chromat Perfecting Cream
A creamy finishing moisturizer that helps seal in hydration and support the skin barrier overnight. It’s an especially beautiful final step when using REGEN PDRN+ as part of an active evening routine.
KrX Aesthetics Sunblocker SPF 50
Daily sun protection is essential in every skincare routine and particularly important when your routine is focused on correcting sun damage and visible signs of aging. Apply every morning to protect against UVA and UVB exposure and help maintain the improvements you’re working toward with REGEN PDRN+ and retinal.
Full Ingredients
Water (Aqua), Salmon Mesenchymal Cell Conditioned Media (Wild Salmon Stem Cell Conditioned Media), Glycerin, Niacinamide, PEG-8/SMDI Copolymer, Sodium DNA, Phenoxyethanol, Butylene Glycol, Carbomer, Momordica Charantia Fruit Extract, Zingiber Officinale (Ginger) Root Extract, Sodium Hyaluronate, Ethylhexylglycerin, Sodium Hydroxide, Mannitol, Dimethylaminoethanol Tartrate, Malus Domestica Fruit Cell Culture Extract, Phosphatidylcholine, Camellia Sinensis (Green Tea) Leaf Extract, Phospholipids, Sodium Phytate, Lactobacillus Ferment, Sodium Lactate, 1,2-Hexanediol, Hyaluronic Acid, Leontopodium Alpinum Meristem Cell Culture, Potassium Sorbate, Sodium Benzoate, Polysorbate 20, Spiraea Ulmaria Flower Extract, Xanthan Gum, Cetyl Alcohol, Decyl Glucoside, Taurine, Centella Asiatica Flower/Leaf/Stem Extract, Maltodextrin, Isomalt, Citric Acid, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Crithmum Maritimum Extract, Gardenia Florida Fruit Extract, Caprylyl Glycol, Coffea Arabica (Coffee) Seed Extract, Sodium Chloride, Lecithin, Bis(Tripeptide-1) Copper Acetate, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Arginine, Leucine, Lysine, Valine, Rhododendron Ferrugineum Leaf Cell Culture Extract, Lactic Acid, Dipotassium Phosphate, Oligopeptide-1, Potassium Phosphate, Citrus Paradisi (Grapefruit) Peel Oil, Citrus Sinensis (Orange) Peel Oil, Limonene. (Lira Clinical)
Frequently Asked Questions
Q: What is PDRN in skincare?
A: PDRN (polydeoxyribonucleotide) is a regenerative ingredient derived from purified salmon DNA. It is used in skincare to support the skin’s natural repair processes, collagen production and overall resilience.
Q: Why is REGEN PDRN+ Serum blue?
A: The distinctive blue color comes from Copper Tripeptide-1, a naturally blue copper peptide in the formula. There are no added blue dyes or colorants listed in the formula.
Q: Does PDRN serum smell like fish?
A: Some salmon-derived PDRN products can have a noticeable marine scent. REGEN PDRN+ does not have a strong marine scent. Instead, it has a light essential-oil scent from grapefruit and orange peel oils.
Q: When should I use REGEN PDRN+ Serum?
A: I prefer REGEN PDRN+ in the evening, when the skin’s natural renewal and repair processes are more active. Apply 1–2 drops after cleansing, allow the serum to fully absorb and dry, then continue with the rest of your skincare routine.
A regenerative PDRN serum designed to calm, repair and strengthen skin while improving firmness, hydration, fine lines and loss of elasticity.
Lira Clinical REGEN PDRN+ Serum takes PDRN skincare a step further by combining PDRN (polydeoxyribonucleotide), a regenerative ingredient derived from purified salmon DNA, with Wild Salmon Stem Cell-CM, copper peptides and growth-factor technology.
This lightweight serum supports the skin’s natural repair processes while helping calm visible redness and inflammation, reinforce the skin barrier, and support collagen and elasticity. With continued use, skin looks smoother, firmer and more even, with improved hydration and a softened appearance of fine lines.
It’s especially helpful for skin that feels depleted, dehydrated or stressed by environmental exposure, as well as skin beginning to show changes in firmness, elasticity and texture.
Size: 1 oz
What Makes It Different
Many PDRN serums center primarily around PDRN. REGEN PDRN+ pairs it with Wild Salmon Stem Cell-CM, Lira Clinical’s biotechnology-derived conditioned media created from cultured wild salmon stem cells, along with copper peptides, EGF and additional peptides.
This multi-pathway approach supports the skin’s natural repair response while targeting fine lines, loss of firmness and elasticity, dehydration, redness and uneven tone.
And the serum’s distinctive blue color isn’t just for looks. It comes from Copper Tripeptide-1, a naturally blue peptide, rather than added blue dyes or colorants.
Key Ingredients
PDRN (Polydeoxyribonucleotide)
A regenerative ingredient derived from purified salmon DNA that supports the skin’s natural repair processes while helping promote collagen production and calm visible inflammation.
Wild Salmon Stem Cell-CM
Lira Clinical’s marine-derived conditioned-media technology, created from cultured wild salmon stem cells. It provides regenerative signaling components that support cellular renewal and help strengthen skin resilience.
Copper Tripeptide-1
A naturally blue copper peptide that gives REGEN PDRN+ Serum its distinctive blue color. It supports collagen and elastin to help improve the appearance of firmness and fine lines.
EGF + Peptide Complex
Oligopeptide-1 (EGF) supports skin renewal and barrier function, while additional peptides help support collagen and soften the appearance of expression lines.
Niacinamide
Supports the skin barrier while helping improve uneven tone, hydration and overall skin resilience.
Hyaluronic Acid
Attracts and retains moisture to help keep skin soft, smooth and hydrated.
How to Use
Apply 1–2 drops in the evening after cleansing. Allow the serum to fully absorb and dry before applying additional skincare products.
I prefer using REGEN PDRN+ at night, when the skin’s natural renewal and repair processes are more active.
Pila’s Tip
PDRN products can sometimes have a noticeable marine scent because of their salmon-derived ingredients. REGEN PDRN+ doesn’t have that strong marine scent at all. Instead, it has a light essential-oil scent from grapefruit and orange peel oils.
I especially like this serum for skin that is dehydrated, environmentally stressed or beginning to show fine lines and loss of firmness and elasticity. Its combination of PDRN, copper peptides and regenerative technology makes it an especially interesting addition to an evening skincare routine.
Pairs Well With
Green Envee Retinal Renewal Complex
One of my favorite pairings with REGEN PDRN+. Retinoids are incredibly effective for fine lines, texture and firmness, but the dryness and irritation they can cause can make them difficult to use consistently. REGEN PDRN+ brings PDRN, copper peptides, niacinamide and hyaluronic acid into the routine to support hydration, the skin barrier and natural repair processes while you get the benefits of retinal.
Chromat Perfecting Cream
A creamy finishing moisturizer that helps seal in hydration and support the skin barrier overnight. It’s an especially beautiful final step when using REGEN PDRN+ as part of an active evening routine.
KrX Aesthetics Sunblocker SPF 50
Daily sun protection is essential in every skincare routine and particularly important when your routine is focused on correcting sun damage and visible signs of aging. Apply every morning to protect against UVA and UVB exposure and help maintain the improvements you’re working toward with REGEN PDRN+ and retinal.
Full Ingredients
Water (Aqua), Salmon Mesenchymal Cell Conditioned Media (Wild Salmon Stem Cell Conditioned Media), Glycerin, Niacinamide, PEG-8/SMDI Copolymer, Sodium DNA, Phenoxyethanol, Butylene Glycol, Carbomer, Momordica Charantia Fruit Extract, Zingiber Officinale (Ginger) Root Extract, Sodium Hyaluronate, Ethylhexylglycerin, Sodium Hydroxide, Mannitol, Dimethylaminoethanol Tartrate, Malus Domestica Fruit Cell Culture Extract, Phosphatidylcholine, Camellia Sinensis (Green Tea) Leaf Extract, Phospholipids, Sodium Phytate, Lactobacillus Ferment, Sodium Lactate, 1,2-Hexanediol, Hyaluronic Acid, Leontopodium Alpinum Meristem Cell Culture, Potassium Sorbate, Sodium Benzoate, Polysorbate 20, Spiraea Ulmaria Flower Extract, Xanthan Gum, Cetyl Alcohol, Decyl Glucoside, Taurine, Centella Asiatica Flower/Leaf/Stem Extract, Maltodextrin, Isomalt, Citric Acid, Dipeptide Diaminobutyroyl Benzylamide Diacetate, Crithmum Maritimum Extract, Gardenia Florida Fruit Extract, Caprylyl Glycol, Coffea Arabica (Coffee) Seed Extract, Sodium Chloride, Lecithin, Bis(Tripeptide-1) Copper Acetate, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Arginine, Leucine, Lysine, Valine, Rhododendron Ferrugineum Leaf Cell Culture Extract, Lactic Acid, Dipotassium Phosphate, Oligopeptide-1, Potassium Phosphate, Citrus Paradisi (Grapefruit) Peel Oil, Citrus Sinensis (Orange) Peel Oil, Limonene. (Lira Clinical)
Frequently Asked Questions
Q: What is PDRN in skincare?
A: PDRN (polydeoxyribonucleotide) is a regenerative ingredient derived from purified salmon DNA. It is used in skincare to support the skin’s natural repair processes, collagen production and overall resilience.
Q: Why is REGEN PDRN+ Serum blue?
A: The distinctive blue color comes from Copper Tripeptide-1, a naturally blue copper peptide in the formula. There are no added blue dyes or colorants listed in the formula.
Q: Does PDRN serum smell like fish?
A: Some salmon-derived PDRN products can have a noticeable marine scent. REGEN PDRN+ does not have a strong marine scent. Instead, it has a light essential-oil scent from grapefruit and orange peel oils.
Q: When should I use REGEN PDRN+ Serum?
A: I prefer REGEN PDRN+ in the evening, when the skin’s natural renewal and repair processes are more active. Apply 1–2 drops after cleansing, allow the serum to fully absorb and dry, then continue with the rest of your skincare routine.